hid Antibody

1. hid is required during pupariation for caspase-dependent pruning of class IV da neurons and Nos and Pum delay pruning. PMID: 27256879
2. loss of function mutants shows persisting wing epithelial cells and, furthermore, silencing of the hormone bursicon in the CNS produced collective cell death defective phenotypes manifested in the wing epithelium PMID: 26226435
3. Study provide evidence that miR-6/11 functions through regulation of the proapoptotic genes, reaper (rpr), head involution defective (hid), grim and sickle (skl). PMID: 22095284
4. head involution defect protein and transcripts accumulate specifically in polar cells destined to die PMID: 21113144
5. FoxO targets hid and bim in Drosophila and human, respectively, are responsible for the LRRK2/dLRRK-mediated cell death. PMID: 20624856
6. Rpr is able to self-associate and also binds to Hid and Grim. PMID: 20837774
7. In the Drosophila eye, Ras may protect cells from apoptosis by inhibiting both JNK and Hid activities. PMID: 19840402
8. hid mediates programmed cell death during drosophila development PMID: 11853767
9. Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms. PMID: 12021767
10. Drosophila Bruce can potently suppress Rpr- and Grim-dependent but not Hid-dependent cell death PMID: 12121627
11. head involution defective (Hid)-triggered apoptosis requires caspase-8 but not FADD (Fas-associated death domain) and is regulated by Erk in mammalian cells PMID: 12122017
12. co-expression of Op-IAP3 and the pro-apoptotic Drosophila protein HID resulted in the ubiquitination of HID. PMID: 15325084
13. Both Grim and Hid were demonstrated to interact with Amsacta moorei Entomopoxvirus inhibitor of apoptosis (AMV-IAP) in vivo, and Grim- or Hid-induced cell death was suppressed when AMV-IAP was coexpressed. PMID: 15731262
14. Hid is located downstream of LKB1 and is invloved in LKB1 sependent apoptosis. PMID: 16273080
15. These results show that internal ribosome entry sites-dependent initiation may play a role in the translation of Drosophila proapoptotic genes and suggest a variety of regulatory pathways. PMID: 16794603
16. germ line is maintained through the regulated expression of RHG genes PMID: 17449640
17. Study examined the interactions of the bantam miRNA with the 3' UTR of the hid mRNA and found the potential contribution of the 3-9 seed register to microRNA-mediated gene regulation. PMID: 19286629
18. pro-apoptotic gene hid plays an important role in the execution of cell death in Drosophila. (Review) PMID: 19554451

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KEGG: dme:Dmel_CG5123

STRING: 7227.FBpp0074899

UniGene: Dm.5624