hig Antibody

Code CSB-PA943084XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) hig Polyclonal antibody
Uniprot No.
Target Names
hig
Alternative Names
hig antibody; CG2040 antibody; Locomotion-related protein Hikaru genki antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) hig protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plays a role in the formation of functional neural circuits from the early stages of synapse formation. Has a role in the development of CNS functions involved in locomotor activity.
Gene References into Functions
  1. These data provide insight into how Hasp and Hig construct the synaptic cleft matrix and regulate the differentiation of cholinergic synapses, and also illuminate a previously unidentified architecture within synaptic clefts PMID: 26758847
  2. Hig is a specific component of the synaptic cleft matrix of cholinergic synapses and regulates their postsynaptic organization. PMID: 25319684
Subcellular Location
Secreted.
Tissue Specificity
Expressed in PCC neurons and neuroblasts in the procephalic neurogenic region in the central nervous system. Expressed in nerves running along the surface of the ventral ganglion and that extend to the peripheral tissues. Also expressed in motor nerves an
Database Links

KEGG: dme:Dmel_CG2040

STRING: 7227.FBpp0087688

UniGene: Dm.2241

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