zipt-7.1 Antibody

Code CSB-PA896438XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans zipt-7.1 Polyclonal antibody
Uniprot No.
Target Names
zipt-7.1
Alternative Names
zipt-7.1; hke-4.1; T28F3.3; Zinc transporter zipt-7.1; Histidine-rich membrane protein KE4 homolog 1
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans zipt-7.1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Zinc transporter which regulates intracellular zinc levels. Required for spermatogenesis in both hermaphrodites and males where it resides in an inactive form in immature sperm, spermatids, but is likely activated in response to reduced spe-4 and spe-6 function. Upon activation, mediates the release of zinc from internal stores in spermatids into the cytoplasm. The resulting increase in cytoplasmic zinc levels promotes spermatid activation and subsequent differentiation into mature motile sperm that are capable of fertilization.
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
ZIP transporter (TC 2.A.5) family, KE4/Catsup subfamily
Tissue Specificity
Highly expressed in developing spermatids (at the protein level). Expressed in the germline.
Database Links

KEGG: cel:CELE_T28F3.3

STRING: 6239.T28F3.3

UniGene: Cel.12267

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