hlh-3 Antibody

Datasheet

Code	CSB-PA979049XA01CXY
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans hlh-3 Polyclonal antibody

Uniprot No.

Q22717

Target Names

hlh-3

Alternative Names

hlh-3 antibody; T24B8.6 antibody; Helix-loop-helix protein 3 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans hlh-3 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Probable transcriptional regulator. May mediate transcriptional activation by binding to the E-box motif 5'-CANNTG-3'. Plays a role in the differentiation of the hermaphrodite-specific motor neurons (HSN) that are required for normal egg laying. Might play a role in serotonin production by regulating expression of the tryptophan hydrolase tph-1 which catalyzes serotonin synthesis, in the HSN neurons. Also plays a role in HSN axon guidance towards the vulva and the ventral nerve cord, possibly by promoting the expression of the netrin receptor unc-40. Under feeding conditions, involved in the regulation of the srh-234 chemoreceptor encoding gene expression in the ADL sensory neurons. Together with hlh-2, involved in the induction of programmed cell death in the sister cells of the serotonergic neurosecretory motor (NSM) neurons, probably through the activation of egl-1 transcription.

Gene References into Functions

The role of hlh-3 in nervous system development, is characterized. PMID: 18586090

Subcellular Location

Nucleus.

Tissue Specificity

Expressed in the ADL sensory neurons.

Database Links

KEGG: cel:CELE_T24B8.6

STRING: 6239.T24B8.6

UniGene: Cel.19701

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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