pb Antibody

Code CSB-PA335617XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) pb Polyclonal antibody
Uniprot No.
Target Names
pb
Alternative Names
pb antibody; CG31481 antibody; Homeotic protein proboscipedia antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) pb protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Controls development of mouthparts, and labial and maxillary palps.
Gene References into Functions
  1. Study shows that the LASCY, DYTQL, NANGE motifs, and the C-terminal domain of SCR mediate suppression of induction of ectopic proboscis identity, which would explain why co-expression of PB and SCR is unable to induce ectopic proboscises. PMID: 24121940
  2. The direct functional antagonism between PB and EY (eyeless) proteins suggests a novel crosstalk mechanism integrating known selector functions in head morphogenesis. PMID: 12490563
  3. phenotypic analysis of the pb nonsense or frameshift alleles suggests that the C-terminus is an important region required for maxillary palp and proboscis development PMID: 15190377
  4. Functions in primary steps of tissue patterning, and leads us to suggest the notion of a homeotic organizer. PMID: 15680366
Subcellular Location
Nucleus.
Protein Families
Antp homeobox family, Proboscipedia subfamily
Database Links
CUSABIO guaranteed quality
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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