Dr Antibody

Datasheet

Code	CSB-PA184477XA01DLU
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) Dr Polyclonal antibody

Uniprot No.

Q03372

Target Names

Alternative Names

Dr antibody; msh antibody; CG1897 antibody; Muscle segmentation homeobox antibody; Protein drop antibody; Protein msh antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) Dr protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Plays a key role in the specification of proneural and promuscular cluster formation. Required for the specification of dorsal and lateral muscle progenitor cells. Regulates development of peripheral nervous system derived from lateral neuroblasts.

Gene References into Functions

cross-repression between Ind and Msh stabilizes the border between intermediate and dorsal tritocerebrum and deutocerebrum, and that both transcription factors are competent to inhibit vnd expression PMID: 20673828
expression is expanded ventrally in ind mutant embryos and Ind protein directly and specifically bound to the msh regulatory DNA, and this interaction was required to limit the ventral boundary of msh expression. PMID: 19795518
Data show that expression of gene msh is invloved in dorsoventral regionalization within the developing brain and truncal nervous system in Drosophilia. PMID: 18683637

Subcellular Location

Nucleus.

Protein Families

Msh homeobox family

Tissue Specificity

Dorsal lateral ectoderm, developing central and peripheral nervous systems and the somatic mesoderm. Expressed in dorsal and lateral muscle preclusters and mesodermal fat body precursors.

Database Links

KEGG: dme:Dmel_CG1897

STRING: 7227.FBpp0084807

UniGene: Dm.1455

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