13 Antibody

Code CSB-PA293900XA01FTP
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Product Details

Full Product Name
Rabbit anti-Escherichia phage T1 (Bacteriophage T1) 13 Polyclonal antibody
Uniprot No.
Target Names
13
Alternative Names
13Holin antibody; Pinholin antibody
Raised in
Rabbit
Species Reactivity
Escherichia phage T1 (Bacteriophage T1)
Immunogen
Recombinant Escherichia phage T1 (Bacteriophage T1) 13 protein
Immunogen Species
Escherichia phage T1 (Bacteriophage T1)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of nanometer-scale pores (pinholes) causing host cell membrane depolarization and endolysin refolding and release into the periplasmic space. Once the pinholin has permeabilized the host cell membrane, the SAR-endolysin is released into the periplasm and breaks down the peptidoglycan layer. Determines the precise timing of host cell lysis. Participates with the SAR-endolysin and the U-spanin protein in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles from the host cell.
Subcellular Location
Host cell inner membrane; Single-pass type II membrane protein.
Database Links

KEGG: vg:2772978

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