HRD3A Antibody

Code CSB-PA926230XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) HRD3A Polyclonal antibody
Uniprot No.
Target Names
HRD3A
Alternative Names
HRD3A antibody; EBS5 antibody; At1g18260 antibody; T10O22.22 antibody; ERAD-associated E3 ubiquitin-protein ligase component HRD3A antibody; AtSel1A antibody; Protein EMS-MUTAGENIZED BRI1 SUPPRESSOR 5 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana HRD3A protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Component of the endoplasmic reticulum (ER) quality control system called ER-associated degradation (ERAD) and involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Functions as an ERAD substrate-recruiting factor that recognizes misfolded proteins for the HRD1 E3 ubiquitin ligase complex. Targets the misfolded LRR receptor kinase BRI1.
Gene References into Functions
  1. Defect in HRD3A of the HRD1/HRD3 complex of the endoplasmic reticulum-associated degradation pathway resulted in alteration of the unfolded protein response PMID: 21187857
Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein Families
Sel-1 family
Database Links

KEGG: ath:AT1G18260

STRING: 3702.AT1G18260.1

UniGene: At.14948

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