SSQ1 Antibody

Datasheet

Code	CSB-PA313238XA01SVG
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Product Details

Full Product Name

Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SSQ1 Polyclonal antibody

Uniprot No.

Q05931

Target Names

SSQ1

Alternative Names

SSQ1 antibody; SSC2 antibody; YLR369W antibody; Heat shock protein SSQ1 antibody; mitochondrial antibody; Stress-seventy subfamily Q protein 1 antibody; mtHSP70 homolog antibody

Raised in

Rabbit

Species Reactivity

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Immunogen

Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SSQ1 protein

Immunogen Species

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria. Assisted by the DnaJ-like co-chaperone JAC1 and the nucleotide exchange factor MGE1, it mediates ATP-dependent Fe-S cluster transfer from the scaffold proteins ISU1/ISU2 to GRX5.

Gene References into Functions

Data show that mitochondrial Hsp70 chaperone Ssq1 interacts with the monothiol glutaredoxin 5 (Grx5) at a binding site different from that of Isu1. PMID: 23615440
the induction of the zim17 mutant phenotype leads to strong import defects for Ssc1-dependent matrix-targeted precursor proteins that correlate with a significantly reduced binding of newly imported substrate proteins to Ssc1. PMID: 24030826
formation of a Jac1-Isu1 complex can overcome a lowered affinity of Ssq1 for Isu in vivo as well as in vitro PMID: 15958384
Ssq1p/Jac1p/Mge1p are not important for Fe/S cluster synthesis on Isu1p PMID: 16431909
Description of the role of ssq1/ssc2 in maturation of yeast frataxin (Yfh1p). PMID: 9660806
Initial description of SSH1 (also referred to as SSC2 and SSQ1) as a mitochondrial heat shock protein 70 (HSP70) of yeast. [SSH1] PMID: 8707841

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Subcellular Location

Mitochondrion matrix.

Protein Families

Heat shock protein 70 family

Database Links

KEGG: sce:YLR369W

STRING: 4932.YLR369W

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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SSQ1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background