HTRA2 Antibody

Datasheet
Code CSB-PA463550XA01DMR
Product Type Polyclonal Antibody
Uniprot No. B4PST0
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Drosophila yakuba (Fruit fly) HTRA2 protein
Raised in Rabbit
Species Reactivity Drosophila yakuba (Fruit fly)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) HtrA2 GE26447
Immunogen Species Drosophila yakuba (Fruit fly)
Gene Names HtrA2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Can antagonize antiapoptotic activity of th by directly inducing the degradation of th (By similarity).
Subcellular Location Mitochondrion intermembrane space, Single-pass membrane protein, Mitochondrion membrane, Single-pass membrane protein
Protein Families Peptidase S1C family
Database Links

KEGG: dya:Dyak_GE26447

STRING: 7245.FBpp0271457

Pathway Apoptosis

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