HUL5 Antibody

Datasheet

Code	CSB-PA346047XA01SVG
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Product Details

Full Product Name

Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) HUL5 Polyclonal antibody

Uniprot No.

P53119

Target Names

HUL5

Alternative Names

HUL5 antibody; YGL141W antibody; Probable E3 ubiquitin-protein ligase HUL5 antibody; EC 2.3.2.26 antibody; HECT-type E3 ubiquitin transferase HUL5 antibody

Raised in

Rabbit

Species Reactivity

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Immunogen

Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) HUL5 protein

Immunogen Species

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Non essential.

Gene References into Functions

Review discusses how the Hul5 protein quality control pathway may specifically target low solubility cytosolic proteins in the cell.[Review] PMID: 22561164
Hul5 is involved in a cytosolic protein quality control pathway that targets misfolded proteins for degradation. PMID: 21983566
support a role for the ATPase subunits in the unfolding of proteasome substrates before insertion into the catalytic cavity and suggest a role for Hul5 in the processive degradation of proteins that are stalled on the proteasome. PMID: 20008553
We report here a proteasome-dependent conjugating activity of Hul5 that endows proteasomes with the capacity to extend ubiquitin chains. PMID: 17190603
Hul5 is required for fragment-specific substrate degradation in endoplasmic reticulum-associated degradation PMID: 18436532

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Database Links

KEGG: sce:YGL141W

STRING: 4932.YGL141W

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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HUL5 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background