ICR1 Antibody

Datasheet

Code	CSB-PA102445XA01DOA
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ICR1 Polyclonal antibody

Uniprot No.

Q8LE98

Target Names

ICR1

Alternative Names

ICR1 antibody; RIP1 antibody; At1g17140 antibody; F20D23.32 antibody; F20D23_31 antibody; Interactor of constitutive active ROPs 1 antibody; ROP-interactive partner 1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana ICR1 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Acts as a scaffold, mediating interaction of ROPs with different proteins. Required for primary and adventitious root maintenance, but not for their formation. Promotes the stabilization of ARAC11 on the plasma membrane of the pollen tube initiation site but not the activation of ARAC11. Regulates directionality of polar auxin transport, and is required for the formation of a stable auxin maximum and tip localized auxin gradient during embryogenesis, organogenesis, and meristem activity. Involved in exocytosis and in the recycling of PIN proteins back to the plasma membrane.

Gene References into Functions

Bimodal regulation of ICR1 levels generates self-organizing auxin distribution. PMID: 25468974
RIP1 is involved in the positive feedback regulation of ROP1 localization to the plasma membrane, leading to the establishment of a polar site for pollen germination and pollen tube growth. [RIP1] PMID: 19825600
ICR1 is part of an auxin regulated positive feedback loop realized by a unique integration of auxin-dependent transcriptional regulation into ROP-mediated modulation of cell polarity. PMID: 20098722
ICR1 interacts with GTP-bound ROPs and is required for cell polarity and differentiation. PMID: 17493810

Subcellular Location

Cell membrane; Peripheral membrane protein. Nucleus.

Protein Families

ICR family

Tissue Specificity

Expressed in mature and germinating pollen. Expressed throughout the embryo but not in the hypophysis and quiescent center (QC). In roots, absent from the QC and the stem cells.

Database Links

KEGG: ath:AT1G17140

STRING: 3702.AT1G17140.1

UniGene: At.48200

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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