IDP2 Antibody

Code CSB-PA010989XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) IDP2 Polyclonal antibody
Uniprot No.
Target Names
IDP2
Alternative Names
IDP2 antibody; YLR174W antibody; L9470.12 antibody; Isocitrate dehydrogenase [NADP] cytoplasmic antibody; IDH antibody; EC 1.1.1.42 antibody; IDP antibody; NADP(+)-specific ICDH antibody; Oxalosuccinate decarboxylase antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) IDP2 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
May function in the production of NADPH for fatty acid and sterol synthesis.
Gene References into Functions
  1. The S. cerevisiae (Sc) Idp1, Idp2, and Idp3 are highly similar to Homo sapiens (Hs) Idh1 and Idh2 (67, 60 and 59% amino acid identity between Sc Idp1, Idp2, and Idp3, and Hs Idh1, respectively), and the arginine residues corresponding to R100 and R132 in Hs Idh1 (Hs Idh2 R140 and R172) are conserved in the corresponding yeast orthologs PMID: 27427385
  2. there is an ancillary role for IDP1 in cellular glutamate synthesis and a role for IDP2 in equilibrating and maintaining cellular levels of isocitrate and alpha-ketoglutarate PMID: 15574419
Subcellular Location
Cytoplasm.
Protein Families
Isocitrate and isopropylmalate dehydrogenases family
Database Links

KEGG: sce:YLR174W

STRING: 4932.YLR174W

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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