IDM1 Antibody

Code CSB-PA169774XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) IDM1 Polyclonal antibody
Uniprot No.
Target Names
IDM1
Alternative Names
IDM1 antibody; ROS4 antibody; At3g14980 antibody; K15M2.12 antibody; Increased DNA methylation 1 antibody; Histone H3 acetyltransferase IDM1 antibody; EC 2.3.1.- antibody; Protein ROS4 antibody; Repressor of silencing 4 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana IDM1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Histone H3 acetyltransferase that binds methylated DNA at chromatin sites lacking histone H3K4 di- or trimethylation and catalyzes H3K18 and H3K23 acetylation. Prevents the transcriptional silencing of transgenes and of some endogenous genes. Requires the presence of IDM2 for efficient H3K18 acetylation, but not for H3K23 acetylation.
Gene References into Functions
  1. Results suggest that IDM2 functions in active DNA demethylation and in antisilencing by regulating IDM1. PMID: 25002145
  2. IDM1 is a regulator of DNA demethylation; it is required for preventing DNA hypermethylation of highly homologous multicopy genes and other repetitive sequences; it binds methylated DNA at chromatin sites lacking histone H3K4 di- or trimethylation and acetylates H3. [IDM1] PMID: 22700931
Subcellular Location
Nucleus.
Tissue Specificity
Expressed in cotyledons and hypocotyls in young seedlings.
Database Links

KEGG: ath:AT3G14980

STRING: 3702.AT3G14980.1

UniGene: At.53322

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