eIF2gamma Antibody

1. the SUUR protein is required for the SU(VAR)3-9 enzyme to bind to the salivary gland polytene chromosomes PMID: 21340745
2. These data indicate a central role for the SU(VAR)3-9 HMTase in heterochromatin-induced gene silencing in Drosophila.SU(VAR)3-9 is the major heterochromatin-specific HMTase in Drosophila. PMID: 11867540
3. role in chromatin organization at the histone gene cluster and in suppression of position-effect variegation PMID: 12524347
4. Developmental and chromosomal defects induced by DNA hypermethylation could be rescued by mutant alleles of the histone H3-K9 methyltransferase gene Su(var)3-9 PMID: 12640138
5. central role of the SU(VAR)3-9 protein in heterochromatic gene silencing PMID: 12723694
6. The full-length SU(VAR)3-9 enzyme transfers two methyl groups to lysine 9 within a histone 3 tail peptide in a nonprocessive manner, requiring the N-terminus for homodimerization and for full activity in vitro. PMID: 15035645
7. displays extensive H3-K9 di- and trimethylation within but also outside pericentric heterochromatin PMID: 15574598
8. Saturation transfer difference NMR measurements were performed to investigate the interaction of S-adenosyl-l-methionine (AdoMet) with SU(VAR)3-9 PMID: 15835908
9. A mutation in SuUR gene results in a decrease in the amount of SU(VAR)3-9 binding sites in autosomes.the SU(VAR)3-9 protein was found in pericentric heterochromatin and at 223 sites on euchromatic arms. PMID: 16607511
10. SU(VAR)3-9, facilitates HP1 binding to chromatin methylated at lysine 9 within the H3 N terminus (H3K9). PMID: 17101786
11. describe how, in double mutants for Su(var)3-9 and Suppressor of Under-Replication genes encoding two structural proteins of heterochromatin, new banded heterochromatic segments appear in all polytene chromosomes PMID: 17640911

Show More

Hide All

KEGG: dme:Dmel_CG43665

STRING: 7227.FBpp0302537

UniGene: Dm.3299