ifb-1 Antibody

Code CSB-PA624308XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans ifb-1 Polyclonal antibody
Uniprot No.
Target Names
ifb-1
Alternative Names
ifb-1 antibody; F10C1.2 antibody; Intermediate filament protein ifb-1 antibody; Cel IF B1 antibody; Intermediate filament protein B1 antibody; IF-B1 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans ifb-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Cytoplasmic intermediate filaments provide mechanical strength to cells. Essential protein, involved in attachment structures in epidermal cells that connect muscles to the external cuticle. Required in morphogenesis and epidermal integrity. Probable component of embryonic epidermal attachment structures. Functions in larval muscle attachment independently of ifa-2.
Gene References into Functions
  1. observations indicate that SUMO regulates cytoplasmic intermediate filament assembly by maintaining a cytoplasmic pool of nonpolymerized IFB-1, and that this is necessary for normal IFB-1 function. PMID: 19922876
Subcellular Location
Cytoplasm.
Protein Families
Intermediate filament family
Tissue Specificity
Expressed in epidermal cells. Expressed in amphid sensory neurons, the excretory cells, the vulva, the uterus, the rectum and some neurons of the tail. Isoform a and isoform b display a similar pattern of expression. Isoform a is predominant in pharyngeal
Database Links

KEGG: cel:CELE_F10C1.2

STRING: 6239.F10C1.2b

UniGene: Cel.7922

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