ifet-1 Antibody

Code CSB-PA903152XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans ifet-1 Polyclonal antibody
Uniprot No.
Target Names
ifet-1
Alternative Names
ifet-1 antibody; spn-2 antibody; F56F3.1 antibody; Translational repressor ifet-1 antibody; Spindle orientation defective protein 2 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans ifet-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in translational repression of multiple mRNAs in the distal gonad. Recruited to the 3' untranslated region (UTR) of zif-1 by oma-1 and is required for translational repression of zif-1. May also be involved in translational repression of mei-1 through recruitment to the mei-1 3' UTR by oma-1. Required for oogenesis but not spermatogenesis, for P granule formation and for the localization of car-1 and cgh-1 to P granules. Required for normal spindle orientation in early embryos.
Gene References into Functions
  1. these findings suggest that IFET-1 is a key translational regulator and is required for normal P granule formation. PMID: 23264733
Subcellular Location
Cytoplasm.
Tissue Specificity
In the embryo, significantly enriched in the germ cell lineage.
Database Links

KEGG: cel:CELE_F56F3.1

STRING: 6239.F56F3.1

UniGene: Cel.5016

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