ine Antibody

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Code	CSB-PA896135XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) ine Polyclonal antibody

Uniprot No.

Q9VR07

Target Names

ine

Alternative Names

ine antibody; rosA antibody; CG15444 antibody; Sodium- and chloride-dependent GABA transporter ine antibody; Protein inebriated antibody; Protein receptor oscillation A antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) ine protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Plays a role in neuronal membrane excitation, important for normal response properties of the photoreceptor. Able to control excitability from either neurons or glia cells. Ine negatively regulates neuronal sodium channels. Controls neurotransmitter-mediated signaling pathways associated with the structure of the larval peripheral nerve, ine and eag control perineurial glial growth through partially redundant pathways. Isoform A and isoform B are both functional, although isoform A functions with greater efficiency. Has a role in osmolyte transport within the Malpighian tubule and hindgut.

Gene References into Functions

two protein isoforms encoded by the inebriated (ine) gene perform osmolyte transport within the Malpighian tubule and hindgut PMID: 11861562

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family

Tissue Specificity

Expressed both maternally and zygotically. Developing embryos exhibit expression in the posterior hindgut, foregut, midgut, Malpighian tubules, anal plate, Garland cells, and a subset of cells in the central nervous system. Central nervous system expressi

Database Links

KEGG: dme:Dmel_CG15444

STRING: 7227.FBpp0077136

UniGene: Dm.3349

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