INGAP Antibody

Code CSB-PA838804ZA01MRG
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Product Details

Full Product Name
Rabbit anti-Mesocricetus auratus (Golden hamster) INGAP Polyclonal antibody
Uniprot No.
Target Names
INGAP
Alternative Names
Pancreatic beta cell growth factor (Islet neogenesis-associated protein), INGAP
Raised in
Rabbit
Species Reactivity
Mesocricetus auratus
Immunogen
Recombinant Mesocricetus auratus INGAP protein
Immunogen Species
Mesocricetus auratus (Golden hamster)
Conjugate
Non-conjugate
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Constituent of ilotropin, which is a partially purified preparation of cellophane wrapping (CW) pancreata. Capable of initiating duct cell proliferation, a prerequisite for islet neogenesis.
Gene References into Functions
  1. data suggest that human adult pancreatic ductal cells retain morphogenetic plasticity and demonstrate that a short exposure to INGAP triggers their differentiation into insulin-expressing cells in vitro. PMID: 26558987
  2. The results indicate that endogenous INGAP plays a "physiological" positive modulatory role in insulin secretion, supporting its possible use in the treatment of prediabetes and Type 2 diabetes. PMID: 25160856
Subcellular Location
Secreted.
Tissue Specificity
Expressed only in CW animals pancreas and to a lesser extent in duodenum. In pancreas it is found in acinar cells, but not in islets.
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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