INP52 Antibody

Code CSB-PA343514XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) INP52 Polyclonal antibody
Uniprot No.
Target Names
INP52
Alternative Names
INP52 antibody; SJL2 antibody; YNL106C antibody; N2160Polyphosphatidylinositol phosphatase INP52 antibody; Synaptojanin-like protein 2) [Includes: SAC1-like phosphoinositide phosphatase antibody; EC 3.1.3.-); Phosphatidylinositol 4,5-bisphosphate 5-phosphatase antibody; EC 3.1.3.36)] antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) INP52 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Dephosphorylates a number of phosphatidylinositols (PIs) like phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), but also phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Controls the cellular levels and subcellular distribution of phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-bisphosphate. Specifically functions within the early endocytic pathway and actin organization.
Gene References into Functions
  1. A severe motility defect of protein internalization in a codeletant of PIL1 and SJL2 indicates a functional interplay between them in endocytosis PMID: 21872358
  2. Sjl2 is localized to cortical actin patches, sites of endocytosis. PMID: 15798181
Subcellular Location
Cytoplasm, cytoskeleton, actin patch.
Protein Families
Synaptojanin family; Inositol 1,4,5-trisphosphate 5-phosphatase family
Database Links

KEGG: sce:YNL106C

STRING: 4932.YNL106C

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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