in Antibody

Code CSB-PA892878XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) in Polyclonal antibody
Uniprot No.
Target Names
in
Alternative Names
in antibody; CG16993Protein inturned antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) in protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays a role in the definition of cell polarity via the planar cell polarity (PCP) cascade. Acts downstream of fuz and accumulates asymmetrically in wing cells to regulate planar polarity in the wing. Probably acts by regulating ciliogenesis.
Gene References into Functions
  1. Epistatic to frizzled in some, but not all, body regions and cell types. PMID: 11973308
Subcellular Location
Cytoplasm. Cell membrane. Note=Localizes in the vicinity of plasma membrane and the cortical actin cytoskeleton of wing disk and pupal wing cells (PubMed:10570461). Localizes to the proximal side of wing cells, fuz and frtz are required for its localization (PubMed:15556868).
Protein Families
Inturned family
Database Links

KEGG: dme:Dmel_CG16993

STRING: 7227.FBpp0077841

UniGene: Dm.2542

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