zpg Antibody

Code CSB-PA893795XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) zpg Polyclonal antibody
Uniprot No.
Target Names
zpg
Alternative Names
zpg; inx4; CG10125; Innexin inx4; Innexin-4; Protein zero population growth
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) zpg protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Structural component of the gap junctions in germline cells. Required for differentiation and survival of germline cysts in females and of spermatogonia in males; gap junctional communication between spermatogonia and somatic cyst cells may be required for normal differentiation and survival of spermatogonia.
Gene References into Functions
  1. in the male, localizes to the surface of spermatogonia; in the female,localizes to germ cell surfaces PMID: 11973283
  2. innexin 4 was detected in the oolemma up to stage 8 and in nurse-cell membranes up to stage 12. PMID: 19038051
Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Note=Concentrated at the interface between germline and somatic support cells in spermatogonia, early spermatocytes and germ cells in the ovary.
Protein Families
Pannexin family
Tissue Specificity
Expressed in nurse cells and oocyte during oogenesis. Uniform expression in imaginal wing disk and low expression in developing imaginal CNS. Expressed in embryonic pole cells and primordial germ cells.
Database Links

KEGG: dme:Dmel_CG10125

STRING: 7227.FBpp0303218

UniGene: Dm.3496

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