IOS1 Antibody

Code CSB-PA938542XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) IOS1 Polyclonal antibody
Uniprot No.
Target Names
IOS1
Alternative Names
IOS1 antibody; At1g51800 antibody; F19C24.3 antibody; LRR receptor-like serine/threonine-protein kinase IOS1 antibody; EC 2.7.11.- antibody; Protein IMPAIRED OOMYCETE SUSCEPTIBILITY 1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana IOS1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Regulates negatively the abscisic acid (ABA) signaling pathway. Required for full susceptibility to filamentous (hemi)biotrophic oomycetes (e.g. H.arabidopsidis and P.parasitica) and fungal (e.g. E.cruciferarum) pathogens, probably by triggering the repression of ABA-sensitive COLD REGULATED and RESISTANCE TO DESICCATION genes during infection, but independently of immune responses. Involved in BAK1-dependent and BAK1-independent microbe-associated molecular patterns (MAMPs)-triggered immunity (PTI) leading to defense responses, including callose deposition and MAPK cascade activation, toward pathogenic bacteria (e.g. P.syringae). Required for chitin-mediated PTI.
Gene References into Functions
  1. IOS1 participates in fungal pathogen-mediated reprogramming of the Arabidopssi.IOS1 attenuates abscisic acid responses in Arabidopsis. PMID: 25274985
Subcellular Location
Cell membrane; Single-pass membrane protein.
Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family
Tissue Specificity
Expressed in roots, cotyledons, leaves, flowers and siliques.
Database Links

KEGG: ath:AT1G51800

STRING: 3702.AT1G51800.1

UniGene: At.37745

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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