ipaH7.8 Antibody

Code CSB-PA325548XA01SZB
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Product Details

Full Product Name
Rabbit anti-Shigella flexneri ipaH7.8 Polyclonal antibody
Uniprot No.
Target Names
ipaH7.8
Alternative Names
ipaH7.8 antibody; CP0078 antibody; pWR501_0084 antibody; SFLP133 antibody; Probable E3 ubiquitin-protein ligase ipaH7.8 antibody; EC 2.3.2.27 antibody; Probable RING-type E3 ubiquitin transferase ipaH7.8 antibody
Raised in
Rabbit
Species Reactivity
Shigella flexneri
Immunogen
Recombinant Shigella flexneri ipaH7.8 protein
Immunogen Species
Shigella flexneri
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
E3 ubiquitin ligase effector protein that interferes with host's ubiquitination pathway. Functions to alter host cell physiology and promote bacterial survival in host tissues. Catalyzes ubiquitination of mouse Nlrp1b allele 1 protein, releasing the cleaved C-terminal part of Nlrp1b, which polymerizes and forms the Nlrp1b inflammasome followed by host cell pyroptosis.
Subcellular Location
Secreted. Host cytoplasm.
Protein Families
LRR-containing bacterial E3 ligase family
Database Links

KEGG: sfl:CP0078

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