ipaA Antibody

Datasheet

Code	CSB-PA323559XA01SZB
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Target Background

Product Details

Full Product Name

Rabbit anti-Shigella flexneri ipaA Polyclonal antibody

Uniprot No.

P18010

Target Names

ipaA

Alternative Names

ipaA antibody; CP0125 antibody; Invasin IpaA antibody; 70 kDa antigen antibody

Raised in

Rabbit

Species Reactivity

Shigella flexneri

Immunogen

Recombinant Shigella flexneri ipaA protein

Immunogen Species

Shigella flexneri

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Rapidly associates with the first 265 amino acids of vinculin after bacteria-cell contact. This interaction is critical for efficient Shigella uptake. IpaA acts as a potent activator of vinculin and increase its ability to interact with F-actin. The complex IpaA-vinculin induces F-actin depolymerization along with the occasional formation of actin filament bundles.

Gene References into Functions

IpaA has two alpha-helical vinculin-binding sites that simultaneously bind two VD1 molecules. PMID: 16826238

Subcellular Location

Secreted. Note=Secreted through the specialized type-III secretion system Mxi/Spa from the bacterium through the cell cytosol.

Protein Families

SipA/IpaA family

Database Links

KEGG: sfl:CP0125

Promotions

A Special Offer on CUSABIO in Stock Proteins

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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ipaA Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background