ippk Antibody

Code CSB-PA678613XA01DIL
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) ippk Polyclonal antibody
Uniprot No.
Target Names
ippk
Alternative Names
ippk antibody; ipk1 antibody; si:dkey-42i9.3 antibody; zgc:110769 antibody; Inositol-pentakisphosphate 2-kinase antibody; EC 2.7.1.158 antibody; Inositol-1,3,4,5,6-pentakisphosphate 2-kinase antibody; Ins(1,3,4,5,6)P5 2-kinase antibody; InsP5 2-kinase antibody
Raised in
Rabbit
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) ippk protein
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis and ion channel regulation. InsP6 also acts as a key regulator of left-right asymmetry in embryo, probably by regulating asymmetric Ca(2+) during left-right specification.
Gene References into Functions
  1. Inositol 1,3,4,5,6-pentakisphosphate 2-kinase (Ipk1), which generates inositol hexakisphosphate, is critical for normal LR axis determination in zebrafish PMID: 15992547
  2. Ipk1 plays a previously uncharacterized role in ciliary function PMID: 18056639
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
IPK1 type 2 family
Tissue Specificity
Expressed both maternally and zygotically. Expressed in cleavage-stage embryos. Ubiquitously distributed throughout blastula stages of embryogenesis. At the onset of gastrulation, it is enriched in cells around the blastoderm margin. At shield stage, expr
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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