IQD1 Antibody

Code CSB-PA871049XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) IQD1 Polyclonal antibody
Uniprot No.
Target Names
IQD1
Alternative Names
IQD1 antibody; At3g09710 antibody; F11F8.30Protein IQ-DOMAIN 1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana IQD1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins. Modulates expression of glucosinolate pathway genes. May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level. Recruits KLCR1 and calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking.
Gene References into Functions
  1. Data show that the 33 members of the calmodulin (CaM)-interacting plant-specific IQ67 DOMAIN (IQD) family proteins differentially localize, using green fluorescent protein (GFP)-tagged proteins, to multiple and distinct subcellular sites, including including microtubule (MT) arrays, plasma membrane subdomains, and nuclear compartments. PMID: 28115582
  2. In vivo binding to calmodulin and kinesin light chain-related protein-1 suggests a Ca2+-regulated scaffolding function of IQD1 in kinesin motor-dependent transport of multiprotein complexes. PMID: 23531692
  3. IQD1 may act as a scaffold protein recruiting cargo to kinesin motors (KLCR1) for directional transport along microtubules. PMID: 23204523
  4. It was proposed that IQD1 to be novel nuclear factor that integrates intracellular Ca(2+) signals to fine-tune glucosinolate accumulation in response to biotic challenge. PMID: 15960618
  5. IQD proteins link calcium signaling pathways to the regulation of gene expression. PMID: 16368012

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Subcellular Location
Nucleus. Nucleus, nucleolus. Cytoplasm, cytoskeleton.
Protein Families
IQD family
Tissue Specificity
Expressed in roots, flowers, stems, siliques, inflorescence stems and whole shoots. Restricted to the vascular bundles.
Database Links

KEGG: ath:AT3G09710

STRING: 3702.AT3G09710.2

UniGene: At.50163

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