IRE1 Antibody

Datasheet

Code	CSB-PA870168XA01OFG
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Oryza sativa subsp. japonica (Rice) IRE1 Polyclonal antibody

Uniprot No.

Q7XIT1

Target Names

IRE1

Alternative Names

IRE1 antibody; Os07g0471000 antibody; LOC_Os07g28820 antibody; OJ1103_E04.109 antibody; OsJ_24190 antibody; Serine/threonine-protein kinase/endoribonuclease IRE1 antibody; Endoplasmic reticulum-to-nucleus signaling 1 antibody; Inositol-requiring protein 1 antibody; OsIRE1) [Includes: Serine/threonine-protein kinase antibody; EC 2.7.11.1); Endoribonuclease antibody; EC 3.1.26.-)] antibody

Raised in

Rabbit

Species Reactivity

Oryza sativa subsp. japonica (Rice)

Immunogen

Recombinant Oryza sativa subsp. japonica (Rice) IRE1 protein

Immunogen Species

Oryza sativa subsp. japonica (Rice)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Involved in endoplasmic reticulum (ER) stress response. Senses unfolded proteins in the lumen of the ER via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices bZIP50 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response (UPR) transcriptional activator, which then induces transcription of UPR target genes, such as luminal-binding protein (BiP) chaperones.

Gene References into Functions

Expression of some genes encoding pathogenesis-related secretory proteins is reduced by the endoplasmic reticulum stress response mediated by the stress sensor IRE1. PMID: 22993695

Subcellular Location

Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Protein Families

Protein kinase superfamily, Ser/Thr protein kinase family

Tissue Specificity

Expressed in roots, nodes, internodes, leaf sheaths, leaf blades, young ears and mature ears.

Database Links

KEGG: osa:4343198

STRING: 39947.LOC_Os07g28820.1

UniGene: Os.427

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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