irk-1 Antibody

Code CSB-PA346354XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans irk-1 Polyclonal antibody
Uniprot No.
Target Names
irk-1
Alternative Names
irk-1; irk-4; R03E9.4; Inward rectifier potassium channel irk-1
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans irk-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Required for modulation of the activity of the hermaphrodite-specific neurons (HSNs) by the G-protein coupled neuropeptide receptor egl-6 which in turn controls egg-laying behavior.
Subcellular Location
Membrane; Multi-pass membrane protein. Perikaryon. Cell projection. Note=Detected in perikarya and neurites of HSNs.
Protein Families
Inward rectifier-type potassium channel (TC 1.A.2.1) family
Tissue Specificity
Expressed in neurons in the head and tail with no expression detected in non-neuronal cells in these regions. Also detected in the egg-laying system of adult hermaphordites with strong expression in the HSN motor neurons and weak expression in vulval musc
Database Links

KEGG: cel:CELE_R03E9.4

STRING: 6239.R03E9.4

UniGene: Cel.39258

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