CHR11 Antibody

Code CSB-PA837286XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CHR11 Polyclonal antibody
Uniprot No.
Target Names
CHR11
Alternative Names
CHR11 antibody; At3g06400 antibody; F24P17.13 antibody; ISWI chromatin-remodeling complex ATPase CHR11 antibody; EC 3.6.4.- antibody; ISW2-like antibody; Protein CHROMATIN REMODELING 11 antibody; Sucrose nonfermenting protein 2 homolog antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana CHR11 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Possesses intrinsic ATP-dependent nucleosome-remodeling activity. Constitutes the catalytic subunit of several complexes capable of forming ordered nucleosome arrays on chromatin. Involved in the formation of nucleosome distribution patterns. Involved in nuclear proliferation during megagametogenesis and cell expansion in the sporophyte. Required for the maintenance of the plant vegetative phase. In association with RLT1 or RLT2 may prevent the early activation of the vegetative-to-reproductive transition by regulating key genes that contribute to flower timing, such as FT, SEP1, SEP3, AGL8/FUL, SOC1 and FLC. Necessary to acquire heat stress (HS) memory.
Gene References into Functions
  1. AtISWI is involved in the formation of the evenly spaced pattern of nucleosome arrangement in gene bodies-this pattern is associated with high transcriptional levels of genes.[review] PMID: 28213686
  2. Data indicate that double mutations in the AtISWI genes, CHROMATIN REMODELING 11 (CHR11) and CHR17, resulted in the loss of the evenly spaced nucleosome pattern in gene bodies. PMID: 24606212
  3. AtISWI proteins, CHR11 and CHR17, and RLTs represent a previously unrecognized genetic pathway that is required for the maintenance of the plant vegetative phase. [CHR11] PMID: 22694359
  4. Essential for haploid nuclear proliferation during megagametogenesis and cell expansion during the sporophytic phase of the plant life cycle [CHR11] [CHROMATIN REMODELING COMPLEX subunit 11] PMID: 16286646
Subcellular Location
Nucleus.
Protein Families
SNF2/RAD54 helicase family, ISWI subfamily
Tissue Specificity
Highly expressed in growing tissues such as inflorescence and flower meristems, young leaves and floral organs. Expressed in roots, rosette and cauline leaves, stems, flowers, inflorescences and siliques.
Database Links

KEGG: ath:AT3G06400

STRING: 3702.AT3G06400.3

UniGene: At.28209

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