JASON Antibody

Code CSB-PA131544XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) JASON Polyclonal antibody
Uniprot No.
Target Names
JASON
Alternative Names
JASON antibody; At1g06660 antibody; F12K11.5 antibody; Protein JASON antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana JASON protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required for normal spindle orientation at male meiosis II and normal formation of tetrad of microspores. Acts as positive regulator of PS1 in male sporogenesis. Not involved in female meiosis.
Gene References into Functions
  1. Leaky ribosome scanning and alternative translation initiation sites (TISs) likely leads to the formation of two forms of JAS: a long version with an N-terminal Golgi localization signal and a short version with a different N-terminal signal targeting the protein to the plasma membrane. The ratio of the long and short forms of JAS is developmentally regulated. PMID: 28922756
  2. A detailed examination of two mutants, jason and ps1, has been reported, in which disturbed spindle position during male meiosis II results in the incorporation of previously separated chromosome groups into a single cell. PMID: 25757555
  3. JASON positively regulates AtPS1 expression, allowing the proper organization and orientation of metaphase II spindle plates in meiosis II.[JASON] PMID: 21257792
Database Links

KEGG: ath:AT1G06660

STRING: 3702.AT1G06660.1

UniGene: At.26217

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