jing Antibody

Code CSB-PA755473XA01DLU
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Product Details

Full Product Name Rabbit anti-Drosophila melanogaster (Fruit fly) jing Polyclonal antibody
Uniprot No. Q7KHG2
Target Names jing
Alternative Names jing antibody; rhumba antibody; CG9397 antibody; CG9403 antibody; Zinc finger protein jing antibody; Zinc finger protein rhumba antibody
Raised in Rabbit
Species Reactivity Drosophila melanogaster (Fruit fly)
Immunogen Recombinant Drosophila melanogaster (Fruit fly) jing protein
Immunogen Species Drosophila melanogaster (Fruit fly)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

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Target Background

Function
(From Uniprot)
May functionally interact with Polycomb group (PcG) and trithorax group (trxG) proteins to repress transcription (Probable). Required for Egfr pathway function and MAPK activity in CNS midline and tracheal placodes and for CNS axon development and tracheal tubule development. Required to establish the primary axon scaffold in the brain and for lateral positioning of longitudinal glia, longitudinal axons and neurons. Required for glial survival. Required to establish the proximo-distal axis of the developing leg and for wing vein and alula development. Required for regenerative growth in leg imaginal disks. Required for the initiation of anterior migration of border cells of the ovary.
Gene References into Functions
  1. Jing acts as a key transcriptional control element in wiring of the circuitry in the developing olfactory sensory system in Drosophila PMID: 23810656
  2. Study demonstrates that jing is required for btl expression in the branching trachea and dominantly interacts with known regulators of btl expression, including the ETS and POU transcription factors, pointed, and drifter/ventral veinless, respectively. PMID: 21061018
  3. Study shows that jing is a direct downstream target of Trh/Tgo and that Vvl and Pnt are also involved in jing tracheal activation. PMID: 21061019
Subcellular Location Nucleus.
Protein Families AEBP2/jing C2H2-type zinc-finger family
Tissue Specificity Expressed in the imaginal disks of the leg and wing.
Database Links

KEGG: dme:Dmel_CG9397

STRING: 7227.FBpp0112914

UniGene: Dm.5288

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