jkk-1 Antibody

Code CSB-PA445984XA01CXY
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Product Details

Full Product Name Rabbit anti-Caenorhabditis elegans jkk-1 Polyclonal antibody
Uniprot No. G5EDT6
Target Names jkk-1
Alternative Names jkk-1 antibody; F35C8.3 antibody; Dual specificity mitogen-activated protein kinase kinase jkk-1 antibody; MAP kinase kinase jkk-1 antibody; EC antibody; JNK-1 activator kinase antibody; JNK kinase antibody
Raised in Rabbit
Species Reactivity Caenorhabditis elegans
Immunogen Recombinant Caenorhabditis elegans jkk-1 protein
Immunogen Species Caenorhabditis elegans
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

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Target Background

(From Uniprot)
Dual specificity protein kinase which acts as an essential component of the JNK signal transduction pathway. May phosphorylate jnk-1. Plays a role in coordinating locomotion via D-type GABAergic motoneurons and in regulating synaptic vesicle transport downstream of adapter protein unc-16 and probably by activating jnk-1. Positively regulates lifespan. Upon environmental stress such as heat stress regulates daf-16 nuclear translocation probably by activating jnk-1. Regulates germline cell apoptosis in response to heavy metals such as Cu(2+) and to arsenite.
Subcellular Location Cytoplasm. Perikaryon. Cell projection, axon.
Protein Families Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily
Tissue Specificity Expressed in most neurons, including nerve ring, head ganglions, dorsal and ventral nerve cords and tail ganglions.
Database Links

KEGG: cel:CELE_F35C8.3

STRING: 6239.F35C8.3

UniGene: Cel.7913

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