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| Code | CSB-PA445984XA01CXY |
| Size | Enquire |
| Have Questions? | Leave a Message or Start an on-line Chat |
| Full Product Name | Rabbit anti-Caenorhabditis elegans jkk-1 Polyclonal antibody |
| Uniprot No. | G5EDT6 |
| Target Names | jkk-1 |
| Alternative Names | jkk-1 antibody; F35C8.3 antibody; Dual specificity mitogen-activated protein kinase kinase jkk-1 antibody; MAP kinase kinase jkk-1 antibody; EC 2.7.12.2 antibody; JNK-1 activator kinase antibody; JNK kinase antibody |
| Raised in | Rabbit |
| Species Reactivity | Caenorhabditis elegans |
| Immunogen | Recombinant Caenorhabditis elegans jkk-1 protein |
| Immunogen Species | Caenorhabditis elegans |
| Conjugate | Non-conjugated |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification Method | Protein A/G |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Form | Liquid |
| Tested Applications | ELISA, WB (ensure identification of antigen) |
| Protocols | ELISA Protocol |
| Troubleshooting and FAQs | Antibody FAQs |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Value-added Deliverables | ① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control); |
| Quality Guarantee | ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive; |
| Lead Time | Made-to-order (14-16 weeks) |
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| Function (From Uniprot) |
Dual specificity protein kinase which acts as an essential component of the JNK signal transduction pathway. May phosphorylate jnk-1. Plays a role in coordinating locomotion via D-type GABAergic motoneurons and in regulating synaptic vesicle transport downstream of adapter protein unc-16 and probably by activating jnk-1. Positively regulates lifespan. Upon environmental stress such as heat stress regulates daf-16 nuclear translocation probably by activating jnk-1. Regulates germline cell apoptosis in response to heavy metals such as Cu(2+) and to arsenite. |
| Subcellular Location | Cytoplasm. Perikaryon. Cell projection, axon. |
| Protein Families | Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily |
| Tissue Specificity | Expressed in most neurons, including nerve ring, head ganglions, dorsal and ventral nerve cords and tail ganglions. |
| Database Links |
KEGG: cel:CELE_F35C8.3 STRING: 6239.F35C8.3 UniGene: Cel.7913 |
