Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) JMJ30 Polyclonal antibody

Uniprot No.

Q8RWR1

Target Names

JMJ30

Alternative Names

JMJ30 antibody; JMJD5 antibody; At3g20810 antibody; MOE17.12 antibody; Lysine-specific demethylase JMJ30 antibody; AtJMJ30 antibody; EC 1.14.11.- antibody; JmjC domain-containing protein 30 antibody; Jumonji domain-containing protein 5 antibody; AtJMJD5 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana JMJ30 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Target Background

Function

Histone demethylase that demethylates 'Lys-36' (H3K36me) of histone H3 with a specific activity for H3K36me3 and H3K36me2. No activity on H3K36me1. Involved in the control of flowering time by demethylating H3K36me2 at the FT locus and repressing its expression. Acts within the central clock. Works in concert with TOC1 to promote the morning-phased clock genes CCA1 and LHY which function as components of the central oscillator.

Gene References into Functions

The complicated compositions of soybean will be beneficial to the therapy of breast cancer since its causes may be involved in multiple aspects. Soybean represses breast cancer development by downregulating the level of JMJD5. PMID: 30249876
In breast neoplasms, higher expression of JMJD5 was significantly corresponded with clinical stage, histological grade, lymph node metastasis and worse overall survival. PMID: 26617740
JMJ30/AT3G20810 and JMJ32/AT3G45880, two members of the JmjC domain-only group of JMJ proteins, function as H3K27 demethylases and regulate FLC expression. PMID: 25267112
The human homolog of JMJD5, KDM8, has been shown to have histone demethylation activity and is able to partially rescue the plant jmjd5 circadian phenotype. PMID: 21358285
JMJD5 plays an interchangeable role in the timing mechanisms of plants and animals despite their highly divergent evolutionary paths. [JMJD5] PMID: 21115819
Expression of JMJ30 ocillates with a circadian rhythm. Loss of function affects the free-running circadian period. PMID: 21139085

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Subcellular Location

Nucleus. Cytoplasm. Note=Predominantly localized in the nucleus.

Tissue Specificity

Expressed in roots, rosette leaves, stems, inflorescences and siliques.

Database Links

KEGG: ath:AT3G20810

STRING: 3702.AT3G20810.2

UniGene: At.38175

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JMJ30 Antibody

Product Details

Customer Reviews and Q&A

Target Background