JMJ30 Antibody

Code CSB-PA830293XA01DOA
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Product Details

Full Product Name Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) JMJ30 Polyclonal antibody
Uniprot No. Q8RWR1
Target Names JMJ30
Alternative Names JMJ30 antibody; JMJD5 antibody; At3g20810 antibody; MOE17.12 antibody; Lysine-specific demethylase JMJ30 antibody; AtJMJ30 antibody; EC 1.14.11.- antibody; JmjC domain-containing protein 30 antibody; Jumonji domain-containing protein 5 antibody; AtJMJD5 antibody
Raised in Rabbit
Species Reactivity Arabidopsis thaliana
Immunogen Recombinant Arabidopsis thaliana JMJ30 protein
Immunogen Species Arabidopsis thaliana (Mouse-ear cress)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

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Target Background

(From Uniprot)
Histone demethylase that demethylates 'Lys-36' (H3K36me) of histone H3 with a specific activity for H3K36me3 and H3K36me2. No activity on H3K36me1. Involved in the control of flowering time by demethylating H3K36me2 at the FT locus and repressing its expression. Acts within the central clock. Works in concert with TOC1 to promote the morning-phased clock genes CCA1 and LHY which function as components of the central oscillator.
Gene References into Functions
  1. The complicated compositions of soybean will be beneficial to the therapy of breast cancer since its causes may be involved in multiple aspects. Soybean represses breast cancer development by downregulating the level of JMJD5. PMID: 30249876
  2. In breast neoplasms, higher expression of JMJD5 was significantly corresponded with clinical stage, histological grade, lymph node metastasis and worse overall survival. PMID: 26617740
  3. JMJ30/AT3G20810 and JMJ32/AT3G45880, two members of the JmjC domain-only group of JMJ proteins, function as H3K27 demethylases and regulate FLC expression. PMID: 25267112
  4. The human homolog of JMJD5, KDM8, has been shown to have histone demethylation activity and is able to partially rescue the plant jmjd5 circadian phenotype. PMID: 21358285
  5. JMJD5 plays an interchangeable role in the timing mechanisms of plants and animals despite their highly divergent evolutionary paths. [JMJD5] PMID: 21115819
  6. Expression of JMJ30 ocillates with a circadian rhythm. Loss of function affects the free-running circadian period. PMID: 21139085

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Subcellular Location Nucleus. Cytoplasm. Note=Predominantly localized in the nucleus.
Tissue Specificity Expressed in roots, rosette leaves, stems, inflorescences and siliques.
Database Links

KEGG: ath:AT3G20810

STRING: 3702.AT3G20810.2

UniGene: At.38175

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