Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
| Code | CSB-PA011955ZA01HU |
| Size | Enquire |
| Have Questions? | Leave a Message or Start an on-line Chat |
| Full Product Name | Rabbit anti-Homo sapiens (Human) JMJD7 Polyclonal antibody |
| Uniprot No. | P0C870 |
| Target Names | JMJD7 |
| Alternative Names | JMJD7 antibody; Bifunctional peptidase and antibody; 3S)-lysyl hydroxylase JMJD7 antibody; EC 1.14.11.63 antibody; EC 3.4.-.- antibody; JmjC domain-containing protein 7 antibody; Jumonji domain-containing protein 7 antibody; L-lysine antibody; 3S)-hydroxylase JMJD7 antibody |
| Raised in | Rabbit |
| Species Reactivity | Homo sapiens |
| Immunogen | Recombinant Homo sapiens JMJD7 protein |
| Immunogen Species | Homo sapiens (Human) |
| Conjugate | Non-conjugated |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification Method | Protein A/G |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Form | Liquid |
| Tested Applications | ELISA, WB (ensure identification of antigen) |
| Protocols | ELISA Protocol |
| Troubleshooting and FAQs | Antibody FAQs |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Value-added Deliverables | ① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control); |
| Quality Guarantee | ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive; |
| Lead Time | Made-to-order (12-14 weeks) |
There are currently no reviews for this product.
| Function (From Uniprot) |
Bifunctional enzyme that acts both as an endopeptidase and 2-oxoglutarate-dependent monoxygenase. Endopeptidase that cleaves histones N-terminal tails at the carboxyl side of methylated arginine or lysine residues, to generate 'tailless nucleosomes', which may trigger transcription elongation. Preferentially recognizes and cleaves monomethylated and dimethylated arginine residues of histones H2, H3 and H4. After initial cleavage, continues to digest histones tails via its aminopeptidase activity. Additionally, may play a role in protein biosynthesis by modifying the translation machinery. Acts as Fe(2+) and 2-oxoglutarate-dependent monoxygenase, catalyzing (S)-stereospecific hydroxylation at C-3 of 'Lys-22' of DRG1 and 'Lys-21' of DRG2 translation factors (TRAFAC), promoting their interaction with ribonucleic acids (RNA). |
| Gene References into Functions |
|
| Subcellular Location | Nucleus. Cytoplasm. |
| Database Links |
HGNC: 34397 KEGG: hsa:100137047 STRING: 9606.ENSP00000380467 UniGene: Hs.198161 |
