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| Code | CSB-PA991655 |
| Size | US$299 |
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| Have Questions? | Leave a Message or Start an on-line Chat |
| Uniprot No. | P0C870 | ||||||
| Target Names | JMJD7 | ||||||
| Alternative Names |
JMJD7 antibody; Bifunctional peptidase and antibody; 3S)-lysyl hydroxylase JMJD7 antibody; EC 1.14.11.63 antibody; EC 3.4.-.- antibody; JmjC domain-containing protein 7 antibody; Jumonji domain-containing protein 7 antibody; L-lysine antibody; 3S)-hydroxylase JMJD7 antibody
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| Raised in | Rabbit | ||||||
| Species Reactivity | Human,Mouse | ||||||
| Immunogen | Fusion protein of Human JMJD7 | ||||||
| Immunogen Species | Homo sapiens (Human) | ||||||
| Conjugate | Non-conjugated | ||||||
| Isotype | IgG | ||||||
| Purification Method | Antigen affinity purification | ||||||
| Concentration | It differs from different batches. Please contact us to confirm it. | ||||||
| Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | ||||||
| Form | Liquid | ||||||
| Tested Applications | ELISA,IHC | ||||||
| Recommended Dilution |
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| Protocols | ELISA Protocol Immunohistochemistry (IHC) Protocol |
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| Troubleshooting and FAQs | Antibody FAQs | ||||||
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function |
Bifunctional enzyme that acts both as an endopeptidase and 2-oxoglutarate-dependent monoxygenase. Endopeptidase that cleaves histones N-terminal tails at the carboxyl side of methylated arginine or lysine residues, to generate 'tailless nucleosomes', which may trigger transcription elongation. Preferentially recognizes and cleaves monomethylated and dimethylated arginine residues of histones H2, H3 and H4. After initial cleavage, continues to digest histones tails via its aminopeptidase activity. Additionally, may play a role in protein biosynthesis by modifying the translation machinery. Acts as Fe(2+) and 2-oxoglutarate-dependent monoxygenase, catalyzing (S)-stereospecific hydroxylation at C-3 of 'Lys-22' of DRG1 and 'Lys-21' of DRG2 translation factors (TRAFAC), promoting their interaction with ribonucleic acids (RNA).
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| Gene References into Functions |
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| Subcellular Location | Nucleus. Cytoplasm. |
| Database Links |
HGNC: 34397 KEGG: hsa:100137047 STRING: 9606.ENSP00000380467 UniGene: Hs.198161 |
