Name: Jra Antibody
Brand: CUSABIO
SKU: CSB-PA011972XA01DLU

Product Details

Full Product Name	Rabbit anti-Drosophila melanogaster (Fruit fly) Jra Polyclonal antibody
Uniprot No.	P18289
Target Names	Jra
Alternative Names	Jra antibody; jun antibody; CG2275 antibody; Transcription factor AP-1 antibody; Jun-related antigen antibody; dJRA antibody; dJun antibody
Raised in	Rabbit
Species Reactivity	Drosophila melanogaster (Fruit fly)
Immunogen	Recombinant Drosophila melanogaster (Fruit fly) Jra protein
Immunogen Species	Drosophila melanogaster (Fruit fly)
Conjugate	Non-conjugated
Clonality	Polyclonal
Isotype	IgG
Purification Method	Protein A/G
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Tested Applications	ELISA, WB (ensure identification of antigen)
Protocols	ELISA Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables	① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control);
Quality Guarantee	① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive;
Lead Time	Made-to-order (14-16 weeks)

Target Background

Function (From Uniprot)	Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Plays a role in dorsal closure.
Gene References into Functions	Mir-8 modulates Drosophila C virus replication by negative regulation of dJun. PMID: 28691661 Tau and spectraplakin promote synapse formation and maintenance through Jun kinase and neuronal trafficking. PMID: 27501441 Data thus identify Atf3 as a new functional partner of Drosophila Jun during development. PMID: 20023169 study of multisite phosphorylation PMID: 12881422 Fos and Jun, the two components of AP1, are abundantly expressed in motor neurons; a model in which AP1 directly modulates NMJ plasticity processes through a cell autonomous pathway in the motor neuron is supported PMID: 12969508 Src, Jun N-terminal kinase, and STAT pathways are inhibited by Drosophila C-terminal Src kinase, which negatively regulates organ growth and cell proliferation PMID: 15254235 AP1 acts as a repressor by recruiting the deacetylase complex to terminate activation of a group of NF-kappaB target genes PMID: 15640802 AP-1 mediated synapse enhancement and its relationship to increases in synapse number, Ca2+ influx, Ca2+ sensitivity of vesicle fusion or synaptic vesicle number, were examined. PMID: 19228945 Show More Hide All
Subcellular Location	Nucleus.
Protein Families	BZIP family, Jun subfamily
Tissue Specificity	During embryogenesis, expression is elevated in the amnioserosa, in the cells of the dorsolateral epidermis during and following germ-band retraction, in the cells at the leading dorsal edge of the epidermis and in the cells along the cephalic furrow (at
Database Links	KEGG: dme:Dmel_CG2275 STRING: 7227.FBpp0303456 UniGene: Dm.3574

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Jra Antibody

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Code	CSB-PA011972XA01DLU
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