Jra Antibody

Code CSB-PA011972XA01DLU
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Product Details

Full Product Name Rabbit anti-Drosophila melanogaster (Fruit fly) Jra Polyclonal antibody
Uniprot No. P18289
Target Names Jra
Alternative Names Jra antibody; jun antibody; CG2275 antibody; Transcription factor AP-1 antibody; Jun-related antigen antibody; dJRA antibody; dJun antibody
Raised in Rabbit
Species Reactivity Drosophila melanogaster (Fruit fly)
Immunogen Recombinant Drosophila melanogaster (Fruit fly) Jra protein
Immunogen Species Drosophila melanogaster (Fruit fly)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

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Target Background

(From Uniprot)
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Plays a role in dorsal closure.
Gene References into Functions
  1. Mir-8 modulates Drosophila C virus replication by negative regulation of dJun. PMID: 28691661
  2. Tau and spectraplakin promote synapse formation and maintenance through Jun kinase and neuronal trafficking. PMID: 27501441
  3. Data thus identify Atf3 as a new functional partner of Drosophila Jun during development. PMID: 20023169
  4. study of multisite phosphorylation PMID: 12881422
  5. Fos and Jun, the two components of AP1, are abundantly expressed in motor neurons; a model in which AP1 directly modulates NMJ plasticity processes through a cell autonomous pathway in the motor neuron is supported PMID: 12969508
  6. Src, Jun N-terminal kinase, and STAT pathways are inhibited by Drosophila C-terminal Src kinase, which negatively regulates organ growth and cell proliferation PMID: 15254235
  7. AP1 acts as a repressor by recruiting the deacetylase complex to terminate activation of a group of NF-kappaB target genes PMID: 15640802
  8. AP-1 mediated synapse enhancement and its relationship to increases in synapse number, Ca2+ influx, Ca2+ sensitivity of vesicle fusion or synaptic vesicle number, were examined. PMID: 19228945

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Subcellular Location Nucleus.
Protein Families BZIP family, Jun subfamily
Tissue Specificity During embryogenesis, expression is elevated in the amnioserosa, in the cells of the dorsolateral epidermis during and following germ-band retraction, in the cells at the leading dorsal edge of the epidermis and in the cells along the cephalic furrow (at
Database Links

KEGG: dme:Dmel_CG2275

STRING: 7227.FBpp0303456

UniGene: Dm.3574

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