SK Antibody

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Code	CSB-PA748713XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) SK Polyclonal antibody

Uniprot No.

Q7KVW5

Target Names

Alternative Names

SK antibody; CG10706 antibody; Small conductance calcium-activated potassium channel protein antibody; Protein SK antibody; dSK antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) SK protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.

Gene References into Functions

Ca2+ entry at the postsynaptic membrane during spontaneous and evoked transmitter release activated the dSK channel to hyperpolarize the membrane and reduce EPSP amplitude PMID: 24671529
These findings highlight important functions for dSK in courtship memory and suggest that SK channels can mediate multiple forms of behavioral plasticity. PMID: 22509342

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

Potassium channel KCNN family, SK subfamily

Database Links

KEGG: dme:Dmel_CG10706

STRING: 7227.FBpp0303993

UniGene: Dm.11909

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SK Antibody

Product Details

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