Ckb Antibody

1. These results indicate that Hpca associates with BB-CK and that together they translocate to membrane compartments in a Ca(2+)-dependent manner. PMID: 23142228
2. The expression of CK in cochlear tissues during development may reflect differential requirements for creatine-phosphocreatine buffering to replenish ATP consumed during energy-dependent metabolic processes. PMID: 22307408
3. The increase in CKB protein during cerebellar postnatal development was coincident with that of the ubiquitous mitochondrial CK protein and mRNA, indicating that a phosphocreatine energy shuttle probably exists for ATP regeneration in the cerebellum. PMID: 12093362
4. an interaction between KCC2 and brain-type creatine kinase was detected in cultured cells and brain extracts, which might contribute to KCC2-mediated modulation of Cl(-) homeostasis PMID: 15094054
5. CKBB, an energy transduction enzyme, binds to the RNA of the 3'UTR of the faster ATP consuming alphaMyHC. PMID: 15548869
6. In the cellular micro-environment, brain-type creatine kinase activates the KCC2 function. PMID: 16336223
7. Although it is difficult to extrapolate our findings to the human condition, the inhibition of brain CK activity after renal failure may be associated to neuronal loss and may be involved in the pathogenesis of uremic encephalopathy. PMID: 18304734
8. Creatin kinase inhibition caused by cystine released from lysosomes could be one of the mechanisms of tissue damage in patients with cystinosis. PMID: 18418703
9. Total and cytosolic creatine kinase activities were significantly inhibited by Lys. The inhibitory effect of Lys on total cysteine kinase activity was totally prevented by reduced glutathione. PMID: 19370404
10. Results suggest that the inhibition of brain creatine kinase activity may be involved in the pathogenesis of pneumococcal meningitis. PMID: 19409453
11. report the identity of a 45 kDa imidazoline binding protein to be brain creatine kinase and this enzyme possesses an I2 binding site; findings will undoubtedly contribute to greater understanding of and development of imidazoline therapeutic drugs. PMID: 19410564

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KEGG: rno:24264

STRING: 10116.ENSRNOP00000015122

UniGene: Rn.1472