Kdm4B Antibody

Code CSB-PA894185XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Kdm4B Polyclonal antibody
Uniprot No.
Target Names
Kdm4B
Alternative Names
Kdm4B antibody; CG33182Probable lysine-specific demethylase 4B antibody; EC 1.14.11.- antibody; Probable JmjC domain-containing histone demethylation protein 3B antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Kdm4B protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Probable histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate.
Gene References into Functions
  1. Dmp53 enhances the expression of the dKDM4B histone demethylase, which demethylates H3K9me3 preferentially in heterochromatin regions. This mechanism appears to be essential for the proper function of the nucleotide excision repair system. PMID: 20675387
  2. dKDM4B (CG33182) is a homolog of the histone H3K36 demethylase KDM4. PMID: 19061644
Subcellular Location
Nucleus.
Protein Families
JHDM3 histone demethylase family
Database Links

KEGG: dme:Dmel_CG33182

STRING: 7227.FBpp0302636

UniGene: Dm.6975

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