kdpC Antibody

Code CSB-PA361180XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) kdpC Polyclonal antibody
Uniprot No.
Target Names
kdpC
Alternative Names
kdpC; b0696; JW0684; Potassium-transporting ATPase KdpC subunit; ATP phosphohydrolase [potassium-transporting] C chain; Potassium-binding and translocating subunit C; Potassium-translocating ATPase C chain
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) kdpC protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
Gene References into Functions
  1. Data suggest that high-affinity ATP binding to KdpFABC is dependent on conserved Gln in KdpC; that ATP binding to KdpC and ATP hydrolysis by KdpFABC are sensitive to accessibility of ribose hydroxyls; and that KdpC binds with KdpB ATP-binding loop. PMID: 21711450
  2. ATP binding occurred within the Val144-Lys161 peptide located within the C-terminal part of KdpC PMID: 16953591
  3. review K+-translocating KdpFABC complex: KdpC might act as a catalytical chaperone, which cooperatively interacts with the nucleotide to be hydrolyzed PMID: 18058005
Subcellular Location
Cell inner membrane; Single-pass membrane protein.
Protein Families
KdpC family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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