kel Antibody

Datasheet

Code	CSB-PA553802XA01DLU
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) kel Polyclonal antibody

Uniprot No.

Q04652

Target Names

kel

Alternative Names

kel antibody; CG7210Ring canal kelch protein [Cleaved into: Kelch short protein] antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) kel protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Component of ring canals that regulates the flow of cytoplasm between cells. May be involved in the regulation of cytoplasm flow from nurse cells to the oocyte during oogenesis. Binds actin.

Gene References into Functions

results demonstrate that Kelch promotes ring canal cytoskeleton growth primarily through its activity as cullin-RING E3 ubiquitin ligase component PMID: 26384358
demonstrate that association of Drosophila KEL with Cullin-3, likely in a cullin-RING ligase, is essential for the growth of Drosophila female germline ring canals. PMID: 20065088

Subcellular Location

Cytoplasm, cytoskeleton. Note=Inner surface of cytoplasmic bridges or ring canals present in egg chambers. Subcortically in imaginal disk epithelia.

Tissue Specificity

Both proteins are expressed in ovaries, male testis, ovariectomized females, cuticle, salivary gland and imaginal disks. Kelch short protein is the predominant form and is also expressed in fat bodies. On entry into metamorphosis levels of full-length pro

Database Links

KEGG: dme:Dmel_CG7210

STRING: 7227.FBpp0080596

UniGene: Dm.17986

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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