KEX2 Antibody

Code CSB-PA319499XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) KEX2 Polyclonal antibody
Uniprot No.
Target Names
KEX2
Alternative Names
KEX2 antibody; QDS1 antibody; YNL238W antibody; N1122Kexin antibody; EC 3.4.21.61 antibody; Protease KEX2 antibody; Proteinase YSCF antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) KEX2 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Processing of precursors of alpha-factors and killer toxin.
Gene References into Functions
  1. Direct binding of the Kex2p cytosolic tail to the VHS domain of yeast Gga2p facilitates trans-Golgi network to prevacuolar compartment transport and is regulated by phosphorylation. PMID: 23408788
  2. KEX2 gene product plays an important role in proliferation of yeast at low temperatures, which is an important trait of bottom-fermenting brewer's yeast. PMID: 20953094
  3. Proteolytic cleavage occurs in the first extracellular loop of Gef1p at residues KR136/137 and is carried out by the Kex2p protease PMID: 15710404
Subcellular Location
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein Families
Peptidase S8 family, Furin subfamily
Database Links

KEGG: sce:YNL238W

STRING: 4932.YNL238W

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