Kin Antibody

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Code	CSB-PA809097XA01MO
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Product Details

Full Product Name

Rabbit anti-Mus musculus (Mouse) Kin Polyclonal antibody

Uniprot No.

Q8K339

Target Names

Kin

Alternative Names

Kin antibody; Btcd antibody; Kin17DNA/RNA-binding protein KIN17 antibody; Binding to curved DNA antibody; KIN antibody; antigenic determinant of recA protein antibody

Raised in

Rabbit

Species Reactivity

Mus musculus (Mouse)

Immunogen

Recombinant Mus musculus (Mouse) Kin protein

Immunogen Species

Mus musculus (Mouse)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes. May play a role in illegitimate recombination and regulation of gene expression. May participate in mRNA processing. Binds, in vitro, to double-stranded DNA. Also shown to bind preferentially to curved DNA in vitro and in vivo. Binds via its C-terminal domain to RNA in vitro.

Gene References into Functions

This report demonstrates the importance of Kin17 as a critical factor that acts prior to the repair phase of DSB repair and is of bona fide importance for CSR. PMID: 27853268
identification of KIN17 as a component of the human spliceosome indicate that this protein may participate in RNA processing PMID: 15252136

Subcellular Location

Nucleus. Cytoplasm.

Protein Families

KIN17 family

Tissue Specificity

Highly expressed in transformed mouse AtT20 neuroendocrine cells. Expressed at a lower level in testis, kidney, skeletal muscle, liver, lung, spleen, brain and heart and kidney. In testis, expressed at much higher levels in proliferating cells than in dif

Database Links

KEGG: mmu:16588

STRING: 10090.ENSMUSP00000043614

UniGene: Mm.35498

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Kin Antibody

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