klp-20 Antibody

Datasheet

Code	CSB-PA799173XA01CXY
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans klp-20 Polyclonal antibody

Uniprot No.

Q965T6

Target Names

klp-20

Alternative Names

klp-20 antibody; Y50D7A.6 antibody; Kinesin-like protein klp-20 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans klp-20 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Component of the kinesin II motor complex (composed of kap-1 and the heterodimeric motor proteins klp-11 and klp-20) which is required for intraflagellar transport (IFT). Heterodimerizes with klp-11 to form a 'processive' molecular motor upon IFT cargo binding, which, within the kinesin II motor complex, binds to and moves along microtubules in a unidirectional manner (without dissociation of the heterodimer), and in turn, is responsible for the IFT of cargo. Specifically, the kinesin II motor complex, together with the kinesin motor protein osm-3 moves along microtubules and is required for anterograde IFT along the middle segment of the sensory neuron cilia. In particular, the kinesin II motor complex delivers specific ciliary cargo proteins such as che-3 which are related to motility to ciliary tips. This is likely mediated by IFT complexes A and B.

Gene References into Functions

demonstrate that heterodimerization of the two distinct motor domains KLP11 and KLP20 of Caenorhabditis elegans kinesin-2 requires a dimerization seed of merely two heptads at the C terminus of the stalk. PMID: 21917588

Subcellular Location

Cell projection, cilium. Cytoplasm, cytoskeleton.

Protein Families

TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, Kinesin II subfamily

Database Links

KEGG: cel:CELE_Y50D7A.6

STRING: 6239.Y50D7A.6

UniGene: Cel.30872

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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