ATPK1 Antibody

Code CSB-PA337226XA01DOA
Size Enquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ATPK1 Polyclonal antibody
Uniprot No.
Target Names
ATPK1
Alternative Names
ATPK1 antibody; ATPK6 antibody; S6K1 antibody; At3g08730 antibody; F17O14.20Serine/threonine-protein kinase AtPK1/AtPK6 antibody; EC 2.7.11.1 antibody; Ribosomal-protein S6 kinase homolog 1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana ATPK1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway. Mediates the phosphorylation of MRFs (e.g. MRF1).
Gene References into Functions
  1. A 12-amino acid core element in S6 kinase 1 (AtS6K1) was identified as an essential interacting region with Raptor1 protein. PMID: 28285138
  2. identified a 44-amino acid region at the N-terminal end of ribosomal S6 kinase 1 (S6K1) specifically interacted with Raptor1, indicating that this region may contain a functional equivalent of TOS (TOR-Signaling) motif present in mammalian TOR substrates PMID: 26920057
  3. S6K1 interacts with retinoblastoma related protein (RBR)1 via its N-terminal RBR binding motif, promotes its nuclear localization and consequent RBR-dependent repression of cell cycle genes through transcription factor E2FB. PMID: 23531690
  4. Authors propose that TOR functions in polysomes to maintain the active S6K1 (and thus eIF3h) phosphorylation status that is critical for translation reinitiation. PMID: 23524850
  5. The authors found that S6K1 associates with the Retinoblastoma-related 1 (RBR1)-E2FB complex and this is partly mediated by its N-terminal LVxCxE motif. PMID: 20683442
  6. Arabidopsis RAPTOR1 (a TOR regulatory protein) interacts with the HEAT repeats of TOR and that RAPTOR1 regulates the activity of S6 kinase (S6K) in response to osmotic stress [S6K1] PMID: 16377759

Show More

Hide All

Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily
Tissue Specificity
Expressed in all tissues.
Database Links

KEGG: ath:AT3G08730

STRING: 3702.AT3G08730.1

UniGene: At.23700

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1