Raf Antibody

1. Raf-activated intestinal stem cells and their progenies are very sensitive to apoptosis PMID: 26845534
2. Yorkie (Yki), a transcriptional coactivator in the Hippo pathway that regulates organ size, is required for Raf-induced cardiac hypertrophy in flies PMID: 25650441
3. move from the oocyte to the follicle cells in process that does not require endocytosis PMID: 25483249
4. These results suggest that ERK is necessary, but not sufficient, for Raf-mediated cardiac hypertrophy. PMID: 23580199
5. RNAi-mediated inhibition of MAPK-signaling by knockdown of Ras85D, phl/D-Raf or Dsor1/MEK affects larval development, adult life span and hemolymph phosphate, suggesting that some in vivo effects involve activation of this signaling pathway by phosphate. PMID: 23520455
6. role in promotion of blood cell activation and differentiation in conjunction with hopscotch jak kinase PMID: 11919715
7. pTyr 1253 (YE) Neu (ErbB-2) autophosphorylation site signalling requires Raf function. PMID: 12673197
8. the integration of RTK-induced RAS and Src42 signals by CNK as a two-component input is essential for RAF activation PMID: 15660123
9. tyrosine 510 regulates Draf activation by affecting the autoinhibitory interaction between the N- and C-terminal fragments of the protein PMID: 18494562
10. RAF catalytic function is regulated in response to a specific mode of dimerization of its kinase domain, which we term the side-to-side dimer PMID: 19727074

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KEGG: dme:Dmel_CG2845

UniGene: Dm.39