Kr-h1 Antibody

Code CSB-PA362339XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Kr-h1 Polyclonal antibody
Uniprot No.
Target Names
Kr-h1
Alternative Names
Kr-h1 antibody; Kr-h antibody; CG9167Krueppel homolog 1 antibody; Krueppel homologous protein 1 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Kr-h1 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays a general role in the hierarchies of gene expression leading to metamorphosis.
Gene References into Functions
  1. Kr-h1 represses ecdysone biosynthesis by directly inhibiting the transcription of steroidogenic enzymes in both Drosophila and Bombyx. PMID: 29567866
  2. During photoreceptor differentiation, transient repression of Kr-h1 represents a key step regulating neuronal maturation. PMID: 22547825
  3. At the chromosomal level, KR-H localisation is dynamic and that the protein is recruited to, and released from, loci harbouring an important subset of the known regulatory genes as the response advances. PMID: 15661647
  4. KR-H1 has a potential for modulating neuronal morphogenesis, it appears physiologically involved in coordinating general ecdysone signaling. PMID: 17562531
Protein Families
Krueppel C2H2-type zinc-finger protein family
Database Links

KEGG: dme:Dmel_CG45074

STRING: 7227.FBpp0288736

UniGene: Dm.3266

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