KRP6 Antibody

Datasheet

Code	CSB-PA605878XA01DOA
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Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) KRP6 Polyclonal antibody

Uniprot No.

Q0WNX9

Target Names

KRP6

Alternative Names

KRP6 antibody; ACK1 antibody; ICK4 antibody; At3g19150 antibody; MVI11.5Cyclin-dependent kinase inhibitor 6 antibody; Cyclin-dependent kinase inhibitor p22ack1 antibody; Inhibitor/interactor of CDK protein 4 antibody; KIP-related protein 6 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana KRP6 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Binds and inhibits CYCD2-1/CDKA-1 complex kinase activity. Regulates cell division which is crucial for plant growth, development and morphogenesis. May inhibit CDK kinases specifically involved in the G1/S phase transition.

Gene References into Functions

Data suggest the cell cycle uncouples gibberellic acid (GA) and abscisic Acid (ABA) responses in germinating seeds, and that cell cycle regulator KRP6 acts downstream of GA to inhibit mitotic cell cycle activation during germination. PMID: 27021201
KRP6 is involved in multinucleation and acytokinesis occurring in giant-cells. PMID: 25915833
Phosphorylation of KRP6 and KRP7 by SNF1-related protein kinase-1 links plant energy homeostasis and cell proliferation. PMID: 23617622
Results suggest that p22(ack1) and cyclin D1, which act antagonistically, are major rate-limiting factors for cell division in the leaf meristem [p22ack1] PMID: 15464981
ACK1 acts as a cyclin dependent kinase inhibitor in Arabidopsis PMID: 15809079

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Subcellular Location

Nucleus, nucleoplasm. Note=Homogeneously distributed. Present in microspores and accumulates strongly in vegetative cell nuclei immediately after asymmetric division and disappears later.

Protein Families

CDI family, ICK/KRP subfamily

Tissue Specificity

Expressed in newly formed organs such as the shoot apex. Expressed in cotyledon, primary root and marginal region of the leaves as well as in developing pollen.

Database Links

KEGG: ath:AT3G19150

STRING: 3702.AT3G19150.1

UniGene: At.8228

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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KRP6 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background