Kr Antibody

Datasheet

Code	CSB-PA362084XA01DLU
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Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) Kr Polyclonal antibody

Uniprot No.

P07247

Target Names

Alternative Names

Kr antibody; CG3340Protein krueppel antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) Kr protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Krueppel is a gap class segmentation protein. It is involved in the segmentation of the embryo and in the differentiation of the Malpighian tubules.

Gene References into Functions

Surprisingly, the early temporal gene Kruppel acts as one of the sub-temporal genes within the late castor window. PMID: 27740908
Kr regulation can limit the positional variability of the Hb mid-embryo border. PMID: 25793381
Kruppel induction is specific to the loss of Shal, a potassium channel mutant. PMID: 24811378
The segmentation function of Kruppel in Tribolium is fundamentally different from its role in the long-germ embryo of Drosophila. PMID: 16280347
Kr-h1 mediates some of the JH signaling in the adult abdominal epidermis and is upstream of broad protein in this pathway PMID: 18036785
Kruppel tethers the SAP18 bound histone deacetylase complex 1 at distinct enhancer elements, which causes repression via histone H3 deacetylation PMID: 19049982

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Subcellular Location

Nucleus. Note=Chromatin associated.

Protein Families

Krueppel C2H2-type zinc-finger protein family

Database Links

KEGG: dme:Dmel_CG3340

STRING: 7227.FBpp0305365

UniGene: Dm.2786

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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Kr Antibody

Product Details

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Target Background